Danielle Nicole Panabaker was born in Augusta, Georgia. Her younger sister, actress Kay Panabaker, starred in the TV series, Summerland (2004)(WB, 2004-05). Panabaker started acting at a summer camp, before joining community theater productions when she was 10-years-old. Panabaker moved to Naperville, IL, where she was a member of the Neuqua Valley High School speech team. At the age of 14, while most students her age were barely starting their high school career, she graduated.